Single-use duodenoscopes and duodenoscopes with disposable end caps

Area of Science:

• Gastroenterology and Endoscopy
• Infectious Disease Control
• Medical Device Technology

Background:

• Multidrug-resistant infections linked to duodenoscopes pose a global health risk.
• Exogenous patient-to-patient transmission is a significant concern during ERCP procedures.

Framework:

• Review of single-use duodenoscopes, disposable distal ends, and distal end cap sealants.
• Evaluation of technologies aimed at reducing duodenoscope-associated infections.

Implementation:

• Analysis of four duodenoscopes with disposable end caps, one end sheath, and two disposable duodenoscopes.
• Assessment of procedural success, bacterial contamination reduction, clinical outcomes, safety, and cost-effectiveness.

Implications:

• Disposable technologies show promise in eliminating exogenous infections during duodenoscopy.
• Further data on effectiveness, functionality, economics, and environmental impact are crucial for widespread adoption.
• Post-market surveillance and real-world infection analyses are essential for disposable distal end caps.