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Technoscience and Biodiversity Conservation
1ISEM, Univ Montpellier, CNRS, IRD, EPHE, Montpellier, France.
CRISPR gene editing offers powerful tools for conservation, but its application, particularly gene drive, sparks debate. Ethical considerations and public engagement are crucial for responsible deployment in biodiversity conservation efforts.
Area of Science:
- Biotechnology
- Conservation Biology
- Genetics
Background:
- CRISPR/Cas9 gene editing technology enables targeted DNA modification.
- Genome editing, including gene drive, has potential applications in agriculture, public health, and conservation.
Purpose of the Study:
- To review the conflicting views and developments surrounding CRISPR-based genome editing in biodiversity conservation.
- To highlight ethical considerations, conflicts of interest, and public engagement challenges associated with gene drive technology.
Main Methods:
- Literature review of recent developments in CRISPR/Cas9 and gene drive technology.
- Analysis of viewpoints from biodiversity conservation stakeholders.
Main Results:
- Conflicting opinions exist regarding the use of gene drive for conservation, ranging from moratoriums to deployment for invasive species eradication.
- Concerns include financial interests, lobbying, risks, uncertainties, public engagement, and ethical/philosophical questions.
Conclusions:
- The use of gene drive in conservation presents significant ethical challenges and necessitates careful consideration of public perception and scientific communication.
- Further dialogue is required to address the complex relationship between novel biotechnologies and the natural world.
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