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[Long-term consequences of esophageal atresia; esophageal and lung abnormalities in adulthood]

C A Ten Kate1, J Vlot2, L S Kamphuis3

  • 1Erasmus MC-Sophia, afd. Kinderchirurgie, Rotterdam(tevens: Erasmus MC, afd. Maag-, Darm- en Leverziekten, Rotterdam).

Nederlands Tijdschrift Voor Geneeskunde
|March 15, 2021
PubMed

Insights

Adults born with esophageal atresia face increased risks of esophageal cancer and lung issues like bronchiectasis. Early detection by healthcare providers is crucial for improving patient quality of life.

Area of Science:

  • Congenital Malformations
  • Gastroenterology
  • Pulmonology

Background:

  • Esophageal atresia (EA) is a rare congenital anomaly with increasing adult survival rates.
  • Growing adult population with EA necessitates understanding long-term health risks.
  • Long-term complications include Barrett's esophagus, esophageal carcinoma, and lung abnormalities.

Observation:

  • Case 1: A 42-year-old male with unresectable esophageal squamous cell carcinoma.
  • Case 2: A 23-year-old male with Barrett's esophagus, asymptomatic for reflux.
  • Case 3: A 51-year-old female with reflux esophagitis and extensive bronchiectasis due to GERD, chronic aspiration, and tracheomalacia.

Findings:

  • Adults with EA have a higher incidence of esophageal carcinoma and Barrett's esophagus.
  • Lung abnormalities, such as bronchiectasis, are significant comorbidities.
  • These conditions can occur even without typical gastroesophageal reflux symptoms.

Implications:

  • Healthcare providers must maintain high awareness of these potential long-term risks in EA survivors.
  • Early screening and diagnosis are essential for timely intervention.
  • Proactive management can improve the quality of life for individuals with esophageal atresia.

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