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Updated: Nov 12, 2025

Assessing Dyslexia at Six Year of Age
Published on: May 1, 2020
[Executive functions disorders in children with dyslexia]
L S Chutko1, S Yu Surushkina1, E A Yakovenko1
1N. Bekhtereva Institute of Human Brain of the Russian Academy of Sciences, St. Petersburg, Russia.
Children with dyslexia exhibit impaired executive functions, including inattention and impulsivity. Cortexin treatment showed slightly better results than encephabol in improving reading skills and cognitive functions.
Area of Science:
- Neuroscience
- Developmental Psychology
- Pediatrics
Background:
- Children with dyslexia often present with executive function deficits.
- Understanding these deficits is crucial for effective intervention.
Purpose of the Study:
- To investigate executive function disorders in children with dyslexia.
- To evaluate the efficacy of Cortexin in treating these deficits.
Main Methods:
- 60 children with dyslexia (ages 8-11) and 60 controls were assessed.
- Executive functions were evaluated using neurological exams, EEG, and cognitive tests (working memory, attention, impulsivity).
- Dyslexia group received Cortexin or Encephabol; outcomes were compared after one month.
Main Results:
- Children with dyslexia showed higher inattention/impulsivity and lower working memory than controls.
- Both treatments improved reading skills, attention, and working memory.
- Cortexin demonstrated slightly superior efficacy (73.3% improvement) compared to Encephabol (60.0%).
Conclusions:
- Executive function impairments are evident in children with dyslexia.
- Cortexin treatment led to significant neurophysiological changes, suggesting enhanced brain regulatory system activation.
- Cortexin appears to be a promising therapeutic agent for dyslexia-associated executive function deficits.
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