Related Experiment Video
Updated: Nov 12, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
There Is Hope After All: Quantifying Opinion and Trustworthiness in Neural Networks
Mingxi Cheng1, Shahin Nazarian1, Paul Bogdan1
1Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States.
Abstract:
Artificial Intelligence (AI) plays a fundamental role in the modern world, especially when used as an autonomous decision maker. One common concern nowadays is "how trustworthy the AIs are." Human operators follow a strict educational curriculum and performance assessment that could be exploited to quantify how much we entrust them. To quantify the trust of AI decision makers, we must go beyond task accuracy especially when facing limited, incomplete, misleading, controversial or noisy datasets. Toward addressing these challenges, we describe DeepTrust, a Subjective Logic (SL) inspired framework that constructs a probabilistic logic description of an AI algorithm and takes into account the trustworthiness of both dataset and inner algorithmic workings. DeepTrust identifies proper multi-layered neural network (NN) topologies that have high projected trust probabilities, even when trained with untrusted data. We show that uncertain opinion of data is not always malicious while evaluating NN's opinion and trustworthiness, whereas the disbelief opinion hurts trust the most. Also trust probability does not necessarily correlate with accuracy. DeepTrust also provides a projected trust probability of NN's prediction, which is useful when the NN generates an over-confident output under problematic datasets. These findings open new analytical avenues for designing and improving the NN topology by optimizing opinion and trustworthiness, along with accuracy, in a multi-objective optimization formulation, subject to space and time constraints.
Related Concept Videos
Confidence Coefficient
Reliability and Validity
Accuracy and Precision
Accuracy, limits, and approximation
Accuracy is defined as the closeness of the measured value to the true or actual value. In engineering mechanics, repeated measurements are taken during theoretical or experimental analyses to ensure that the result is precise and accurate.
The accuracy of any solution is based on the...
Uncertainty in Measurement: Accuracy and Precision
Interpretation of Confidence Intervals
Confidence intervals have confidence coefficients that are crucial for their interpretation. The most common confidence coefficients are 0.90, 0.95, and 0.99, which can be written as percentages–90%, 95%, and 99%, respectively.
Suppose a person calculates a confidence interval with a confidence coefficient of 0.95. In that case, they can...

