Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Trauma-associated sleep disturbances among women in a nationwide study.

Communications medicine·2026

Same author

A digital health program enhances walking capacity and health status in symptomatic peripheral artery disease.

European heart journal. Digital health·2026

Same author

Recruitment Strategies, Response Rates, and Non-Response Patterns in a Nationwide Registry-Based PRO Survey of Cancer Survivors and the General Population: The SURV-ICE Cohort.

Cancers·2026

Same author

Long-term temporal stability of circulating proteins in older adults.

Nature communications·2026

Same author

Psychological distress and tumor cell β2-adrenergic receptor levels in patients with surgically resected non-small cell lung cancer.

Acta oncologica (Stockholm, Sweden)·2026

Same author

Impact of SARS-CoV-2 vaccination on monoclonal gammopathy of undetermined significance: results from the population-based iStopMM study.

Blood cancer journal·2026

Same journal

Using a Fine-Tuned Commercial Artificial Intelligence Model to Assess Nutrients from Photographs of Japanese Meals.

Journal of diabetes science and technology·2026

Same journal

Diversity of Daily Glycemic Phenotypes Is Independently Associated With HbA1c: A Time-Resolved CGM Clustering Analysis.

Journal of diabetes science and technology·2026

Same journal

Continuous Glucose Monitoring and Early Dysglycemia: Toward an Emerging Stage Preceding Prediabetes.

Journal of diabetes science and technology·2026

Same journal

A Pilot Study on Disposal Practices and Environmental Awareness of Insulin-Related Devices Among People With Diabetes.

Journal of diabetes science and technology·2026

Same journal

Quality of In-Use Insulin Under Real-World Storage Conditions in Mwanza, Tanzania.

Journal of diabetes science and technology·2026

Same journal

Continuous Glucose Monitoring Metrics for Predicting Adverse Neonatal Outcomes in Individuals Undergoing Gestational Diabetes Screening.

Journal of diabetes science and technology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 12, 2025

Control of Eating Behavior Using a Novel Feedback System

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Randomized Trial for Weight Loss Using a Digital Therapeutic Application.

Tryggvi Thorgeirsson^1,2, Johanna E Torfadottir³, Erlendur Egilsson⁴

¹Sidekick Health Digital Therapeutics, Kópavogur, Iceland.

Journal of Diabetes Science and Technology

|March 19, 2021

Summary

This summary is machine-generated.

A digital therapeutic mobile application significantly enhanced weight loss and program attendance in overweight and obese individuals. This smartphone-based intervention shows promise for structured lifestyle change programs.

Keywords:

digital therapeutic intervention study mobile application obesity prediabetes weight loss

More Related Videos

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Related Experiment Videos

Last Updated: Nov 12, 2025

Control of Eating Behavior Using a Novel Feedback System

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Area of Science:

Digital health interventions
Obesity research
Noncommunicable disease prevention

Background:

Smartphones offer a widespread platform for structured lifestyle interventions to mitigate noncommunicable diseases.
This study investigated the efficacy of a digital structured lifestyle program in promoting weight loss.

Purpose of the Study:

To determine if a digital therapeutic mobile application improves weight loss outcomes.
To assess the impact of a digital intervention on adherence to a lifestyle change program.

Main Methods:

Overweight and obese participants were randomized to either standard coaching or standard coaching plus a digital therapeutic mobile application.
The primary outcome was change in body mass index (BMI) after four months.
Odds ratios for achieving 5% weight loss were calculated using logistic regression.

Main Results:

The intervention group using the digital therapeutic showed significant weight loss and BMI reduction (P<0.05).
Participants in the per-protocol intervention group had 3.3 times higher odds of achieving 5% weight loss compared to controls.
Attendance to coaching sessions increased in the intervention group and decreased in the control group (P=0.004).

Conclusions:

A digital therapeutic shows potential for improving weight reduction and engagement in lifestyle change programs.
Further research with larger sample sizes and longer follow-up periods is warranted to validate these findings.