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Updated: Nov 12, 2025
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Management of Nail Psoriasis
Dimitrios Rigopoulos1, Natalia Rompoti2, Stamatios Gregoriou2
1University Hospital of Venereal and Skin Diseases "A.Sygros", 5, Ionos Dragoumi str, Athens 161 21, Greece..
Dermatologic Clinics
|March 22, 2021
Summary
Nail psoriasis treatment depends on severity and patient factors. Mild cases benefit from topical treatments like ointments, while severe cases or those with psoriatic arthritis require systemic therapies for efficacy.
Area of Science:
- Dermatology
- Rheumatology
Background:
- Nail psoriasis is a chronic condition impacting quality of life.
- Personalized treatment strategies are essential for effective management.
Purpose of the Study:
- To outline treatment approaches for nail psoriasis.
- To differentiate between topical and systemic treatment indications.
Main Methods:
- Review of current treatment guidelines for nail psoriasis.
- Categorization of treatment based on disease severity and patient characteristics.
Main Results:
- General prophylactic measures are recommended for all patients.
- Topical treatments (ointments, solutions, foams) are suitable for limited nail involvement (≤3 nails) without significant skin or joint disease.
- Systemic treatments (conventional agents, biologics, small molecules) are indicated for moderate to severe skin psoriasis, psoriatic arthritis, extensive nail disease (>3 nails), or significant quality of life impairment.
Conclusions:
- Treatment selection for nail psoriasis should be individualized.
- Systemic therapies offer high efficacy for more severe presentations of nail psoriasis.
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