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Two-Dimensional Barriers for Probing Conformational Shifts in Macrocycles.

Shinya Kobori1, Sungjoon Huh1, Solomon D Appavoo1

  • 1Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario Canada, M5S 3H6.

Journal of the American Chemical Society
|March 23, 2021
PubMed
Summary

Researchers developed tunable composite barriers in macrocyclic backbones using heterocyclic rearrangements. This method controls conformation and offers insights for new conformational control elements.

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