Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Lateralization

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Self-Reported Inner Speech Reflects Improvement From Language Therapy.

American journal of speech-language pathology·2026

Same author

Narrative Discourse Predictors of Response to Naming Intervention in Aphasia.

Journal of speech, language, and hearing research : JSLHR·2026

Same author

Physical function impacts hearing without mediation from systolic blood pressure.

Scientific reports·2026

Same author

Characterizing Verb Argument Structure in Aphasia Using Dependency Parsers.

Journal of speech, language, and hearing research : JSLHR·2026

Same author

Regional brain atrophy mediates age effects on words recognition in noise in adults.

NeuroImage·2026

Same author

Hypertension-Induced Retinal Microvascular Remodeling in Women.

Journal of vascular research·2026

Same journal

Cross-Subject Event-Related Potential Classification via Multi-View Based Contrastive Learning.

Brain connectivity·2026

Same journal

Clinical Correlates of Resting-State Functional Magnetic Resonance Imaging in Military Personnel with Adulthood-Onset War-Related Post-Traumatic Stress Disorder.

Brain connectivity·2026

Same journal

Meditation Enhances Small-World Network Efficiency: MEG-Based Evidence from Attention and Control Systems.

Brain connectivity·2026

Same journal

Tinnitus Brain: A Functional Reorganization?

Brain connectivity·2026

Same journal

Examining the Neural and Behavioral Impact of Accelerated Intermittent Theta Burst Stimulation in People with Opioid Use Disorder Who Smoke Tobacco Cigarettes: A Pilot Study.

Brain connectivity·2026

Same journal

Fingerprints Beyond Averages: The Temporal Architecture of Individual Brain Connectivity.

Brain connectivity·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 11, 2025

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

Effect of Stroke on Contralateral Functional Connectivity.

Grigori Yourganov¹, Brielle C Stark^2,3, Julius Fridriksson⁴

¹Advanced Computing and Data Science, Cyberinfrastructure and Technology Integration, Clemson University, Clemson, South Carolina, USA.

Brain Connectivity

|March 24, 2021

Summary

This summary is machine-generated.

Brain damage from stroke triggers functional reorganization in the intact hemisphere. Specific brain regions show increased functional connectivity (FC) with greater damage, highlighting localized brain plasticity.

Keywords:

aphasia connectivity fMRI plasticity stroke

More Related Videos

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Published on: August 5, 2014

Related Experiment Videos

Last Updated: Nov 11, 2025

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Published on: August 5, 2014

Area of Science:

Neuroscience
Neurology
Brain Plasticity

Background:

Stroke often leads to significant brain reorganization, but the precise spatial patterns are not well understood.
Understanding how the brain adapts functionally after stroke is crucial for recovery and rehabilitation strategies.

Purpose of the Study:

To systematically investigate the relationship between the location and extent of brain damage and functional connectivity (FC) within the intact hemisphere after stroke.
To identify specific brain regions and networks that exhibit significant changes in FC in response to stroke-induced damage.

Main Methods:

Analysis of functional connectivity (FC) in a large cohort (N=116) of chronic stroke survivors.
Correlation analysis between regional cortical damage and contralateral FC patterns.
Identification of brain regions with the strongest influence on contralateral FC and vice versa.

Main Results:

A significant association was found between brain damage and altered functional connectivity in the contralateral hemisphere.
The majority of identified correlations were positive, indicating increased regional contralateral connectivity with greater damage.
Specific core regions were identified where stroke damage had the most pronounced impact on increasing contralateral network connectivity.

Conclusions:

The brain exhibits a localized capacity for reorganization following stroke, with increased functional connectivity in specific regions of the intact hemisphere.
This increased connectivity appears to be a compensatory mechanism, strengthening with the severity of the damage.
Findings provide novel insights into the spatial patterns and localized nature of adult brain plasticity after stroke.