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Updated: Nov 11, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
[COVID-19 and pregnancy]
Helmut Kleinwechter1, Tanja Groten2, Ute Schäfer-Graf3
1diabetologikum kiel, Diabetesschwerpunktpraxis und Schulungszentrum, Alter Markt 11, 24103 Kiel, Deutschland.
Insights
Pregnant women with diabetes and COVID-19 experienced mostly mild illness, but some required intensive care. Diabetes, particularly type 2, was associated with adverse pregnancy outcomes like fetal death.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Endocrinology
Abstract:
From March 3 to October 13, 2020, 27 cases with diabetes comorbidity have been recorded in the CRONOS registry (Covid-19 Related Obstetric and Neonatal Outcome Study in Germany) among 262 registered women with SARS-CoV‑2 infection during their pregnancy. Of those, 21 presented with gestational diabetes, 5 with type 2 diabetes and 1 with type 1 diabetes. About half of the women were asymptomatic and were diagnosed via general screening at hospital admission. The most common symptoms were nasal congestion, cough, tiredness, malaise and changes in smell and taste. The majority of pregnant women showed a mild to moderate course, three women were admitted to the intensive care unit and none required invasive ventilation. In the type 2 diabetes group, there were two cases with late fetal death (37 and 40 weeks of gestation) and one with a malformation, an association with diabetes being most likely. Pregnant women with diabetes mellitus represent a special subgroup; 1 in 10 women in this small cohort required intensive care monitoring due to COVID-19. In addition, this case series underscores the need for unrestricted access to pregnancy care, especially in times of pandemic, for optimal perinatal outcome.
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