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Epidermal cell renewal in the horse
B B Barker1, A A Stannard, H I Maibach
1Department of Veterinary Clinical Medicine and Surgery, Washington State University, Pullman 99164-6610.
American Journal of Veterinary Research
|April 1, 1988
Summary
This study estimated epidermal cell renewal in horses. The viable epidermis in horses renews approximately every 17 days, with a 1.45% labeling index observed.
Area of Science:
- Veterinary Dermatology
- Equine Biology
- Cell Biology
Background:
- Understanding skin cell turnover is crucial for equine health.
- Epidermal renewal rates vary significantly across species.
Purpose of the Study:
- To determine the epidermal cell labeling index in adult horses.
- To estimate the cell renewal time of the viable equine epidermis.
Main Methods:
- Autoradiography was employed in 8 adult horses.
- [3H]thymidine was administered intradermally to label dividing cells.
Main Results:
- The mean epidermal cell labeling index was found to be 1.45 +/- 0.47%.
- The estimated cell renewal time for the viable epidermis was approximately 17 days.
Conclusions:
- The equine epidermis exhibits a cell renewal time of approximately 17 days.
- This data provides baseline information for equine skin physiology.