Related Experiment Video
Updated: Nov 11, 2025
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Dual-Energy CT Material Decomposition in Pediatric Thoracic Oncology.
Marilyn J Siegel1, Sanjeev Bhalla1, Mike Cullinane1
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St Louis, MO 63110 (M.J.S., S.B.); and Siemens Healthineers, Malvern, Pa (M.C.).
Dual-energy CT (DECT) offers advanced imaging for thoracic oncology in children, providing detailed tissue information without increased radiation exposure. This technology aids in characterizing lung nodules and malignancies, improving diagnosis and treatment assessment.
Area of Science:
- Radiology
- Medical Imaging
- Oncology
Background:
- Computed tomography (CT) technical advancements facilitate routine dual-energy CT (DECT) implementation.
- DECT acquires images at two energy spectra, enabling material decomposition.
- This process generates material- and energy-specific images, including virtual nonenhanced and monoenergetic images.
Purpose of the Study:
- To highlight the advantages of DECT in thoracic oncologic imaging, particularly in pediatric patients.
- To demonstrate DECT's utility in characterizing thoracic malignancies and lung nodules.
- To assess DECT's role in determining disease extent and response to therapy.
Main Methods:
- Acquisition of dual-energy CT datasets.
- Generation of material-specific images (virtual nonenhanced, iodine maps).
- Generation of energy-specific images (virtual monoenergetic images).
Main Results:
- DECT provides unique qualitative and quantitative data on tissue composition and contrast media distribution.
- DECT enhances characterization of thoracic malignancies and lung nodules.
- DECT aids in assessing disease extent and treatment effects in thoracic oncology.
- DECT does not increase radiation exposure in pediatric patients.
Conclusions:
- Dual-energy CT is a valuable tool in pediatric thoracic oncology.
- DECT improves the characterization of thoracic malignancies and lung nodules.
- DECT offers advantages in assessing disease extent and treatment response without additional radiation.
More Related Videos
09:49Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Published on: December 2, 2013
08:17Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
Related Concept Videos
01:10Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
01:24X-ray Imaging
01:29Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
01:30Radiological Investigation I: X-ray and CT
01:30Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...