Sarcoidosis Causing Complete Nasal Obstruction

Area of Science:

• Otorhinolaryngology
• Pulmonology
• Immunology

Background:

• Sarcoidosis is a multisystem granulomatous disease of unknown etiology.
• Pulmonary involvement is most common, but sinonasal disease can occur.
• Systemic sarcoidosis can present with diverse and rare manifestations.

Observation:

• A patient with a remote history of pulmonary sarcoidosis, in remission, presented with severe nasal obstruction.
• No prior history of sinonasal sarcoidosis was noted.
• Physical examination revealed significant nasal blockage attributed to the disease.

Findings:

• The case demonstrates a rare presentation of sinonasal sarcoidosis.
• This manifestation led to severe nasal obstruction despite remission of pulmonary sarcoidosis.
• Histopathological examination confirmed granulomatous inflammation consistent with sarcoidosis.

Implications:

• Sinonasal sarcoidosis should be considered in the differential diagnosis of nasal obstruction.
• A history of systemic sarcoidosis increases suspicion for sinonasal involvement.
• Early recognition and diagnosis are crucial for managing sinonasal sarcoidosis and preventing complications.