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This case highlights rare sinonasal sarcoidosis causing severe nasal obstruction. Consider sarcoidosis in nasal obstruction, particularly with a history of systemic sarcoid disease.

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Area of Science:

  • Otorhinolaryngology
  • Pulmonology
  • Immunology

Background:

  • Sarcoidosis is a multisystem granulomatous disease of unknown etiology.
  • Pulmonary involvement is most common, but sinonasal disease can occur.
  • Systemic sarcoidosis can present with diverse and rare manifestations.

Observation:

  • A patient with a remote history of pulmonary sarcoidosis, in remission, presented with severe nasal obstruction.
  • No prior history of sinonasal sarcoidosis was noted.
  • Physical examination revealed significant nasal blockage attributed to the disease.

Findings:

  • The case demonstrates a rare presentation of sinonasal sarcoidosis.
  • This manifestation led to severe nasal obstruction despite remission of pulmonary sarcoidosis.
  • Histopathological examination confirmed granulomatous inflammation consistent with sarcoidosis.

Implications:

  • Sinonasal sarcoidosis should be considered in the differential diagnosis of nasal obstruction.
  • A history of systemic sarcoidosis increases suspicion for sinonasal involvement.
  • Early recognition and diagnosis are crucial for managing sinonasal sarcoidosis and preventing complications.