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Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy
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Complexity-guided Fourier phase retrieval from noisy data.

Mansi Butola, Sunaina Rajora, Kedar Khare

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    |April 2, 2021
    PubMed
    Summary
    This summary is machine-generated.

    Recovering phase information from noisy data is difficult. A new complexity-guided strategy improves phase retrieval by controlling solution complexity during hybrid input-output (HIO) iterations, offering robust performance with increasing noise.

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    Area of Science:

    • Optics
    • Image Processing
    • Computational Science

    Background:

    • Phase retrieval from single-shot Fourier intensity data is crucial but challenging, especially with noise.
    • Existing algorithms like hybrid input-output (HIO) struggle with noisy datasets, leading to unstable solutions.

    Purpose of the Study:

    • To investigate the behavior of HIO algorithm solutions with noisy data.
    • To develop and test a novel complexity guidance strategy for robust phase retrieval.
    • To enhance the stability and quality of reconstructed solutions from noisy Fourier intensity data.

    Main Methods:

    • Examined HIO algorithm performance on noisy Fourier intensity data.
    • Introduced and applied a complexity guidance methodology to control solution complexity.
    • Actively tracked and managed the growth of solution complexity inside and outside the defined support region during HIO iterations.
    • Tested the strategy with Poisson noise across a wide range of photon counts.

    Main Results:

    • Observed increasing solution complexity outside the support with HIO iterations for noisy data.
    • Demonstrated that the proposed strategy effectively controls solution complexity, improving phase retrieval quality.
    • The strategy showed noise robustness, with gradual quality degradation as noise increased.
    • Main object features were retained even at higher noise levels, though textural details were lost.
    • Successfully handled pure phase objects, mixed amplitude-phase objects, and data with blocked DC components.

    Conclusions:

    • The developed complexity guidance strategy offers a robust method for phase retrieval from noisy single-shot Fourier intensity data.
    • This approach enhances the stability and quality of reconstructed solutions, outperforming standard HIO for noisy datasets.
    • The findings have broad applicability in fields requiring critical single-shot Fourier phase retrieval.