Related Experiment Video
Updated: Nov 10, 2025

13:04
Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
Published on: May 16, 2019
38.9K
Exploratory Study: Excessive Iron Supplementation Reduces Zinc Content in Pork without Affecting Iron and Copper
Maureen Middleton1, Manuel Olivares1, Alejandra Espinoza2
1Laboratorio de Micronutrientes, Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile, Av El Libano 5524, Macul, Santiago 7830490, Chile.
Animals : an Open Access Journal From MDPI
|April 3, 2021
Summary
Excessive iron supplementation in pigs improved iron status but significantly reduced zinc levels in pork meat. Offal mineral content remained largely unaffected by high iron diets.
Area of Science:
- Animal Nutrition
- Mineral Metabolism
- Meat Science
Background:
- Optimizing mineral levels in livestock is crucial for animal health and meat quality.
- Understanding the impact of excessive mineral supplementation is essential to prevent potential adverse effects.
Purpose of the Study:
- To investigate the effects of high dietary iron levels on iron, zinc, and copper concentrations in pork and its offal.
- To assess the impact of excessive iron on iron biomarkers and mineral status in pigs.
Main Methods:
- Pigs were fed diets with either 500 ppm (control) or 3000 ppm (supplemental) iron for 60 days.
- Blood samples were analyzed for iron biomarkers, serum zinc, and copper.
- Mineral content (iron, zinc, copper) was determined in nine meat cuts and various offal samples post-slaughter.
Main Results:
- Iron supplementation increased hemoglobin and hematocrit, indicating improved iron status.
- Serum iron, zinc, and copper levels were not significantly affected by high iron intake.
- Zinc content in pork meat cuts decreased by 32-55%, while iron content increased in liver, spleen, kidneys, and pancreas. Offal zinc and copper levels showed no significant changes.
Conclusions:
- High dietary iron supplementation effectively improves iron status in pigs.
- Excessive iron intake leads to a significant reduction in zinc concentration in pork meat.
- Iron supplementation does not alter zinc and copper levels in pork offal.
Related Concept Videos
The Periodic Table and Organismal Elements
194.5K
Overview
194.5K
The Periodic Table and Organismal Elements
21.3K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
Periodic Table Provides Information...
21.3K
Necrosis
5.2K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
5.2K
Extraction: Advanced Methods
758
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
758

