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Updated: Nov 10, 2025
A Piglet Model of Neonatal Hypoxic-Ischemic Encephalopathy
Published on: May 16, 2015
Extubation Readiness in Preterm Infants: Evaluating the Role of Monitoring Intermittent Hypoxemia
Elie G Abu Jawdeh1, Amrita Pant2, Aayush Gabrani3
1Division of Neonatology, Department of Pediatrics, College of Medicine, University of Kentucky, Lexington, KY 40508, USA.
Abstract:
Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.
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