Advances in Molecularly Imprinted Polymers Based Affinity Sensors (Review)

Area of Science:

• Materials Science
• Analytical Chemistry
• Biomedical Engineering

Background:

• Biomedical diagnostics face challenges requiring rapid affinity sensors.
• Polymer-based semiconducting materials are crucial for developing advanced sensors.

Purpose of the Study:

• To review the application of polymer-based semiconducting materials in affinity sensors.
• To highlight progress in material development and their bioanalytical applications.

Main Methods:

• Overview of conducting polymers like polypyrrole, polyaniline, and polythiophene.
• Discussion of polymerization techniques for composite structures.
• Exploration of molecular imprinting technology and signal transduction methods.

Main Results:

• Conducting polymers show significant potential in designing affinity sensors.
• Molecularly imprinted polymers can serve as cost-effective alternatives to antibodies and receptors.
• Electrochromic polymers and biocompatible coatings offer new design possibilities.

Conclusions:

• Polymer-based semiconducting materials are vital for next-generation affinity sensors.
• Future applications include implantable sensors with enhanced biocompatibility.
• This review highlights emerging trends in analytical applications of these materials.