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Updated: Nov 10, 2025
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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
18.4K
Radiosurgery, reirradiation, and brachytherapy.
Dheerendra Prasad1, Tamara Vern-Gross2, Suzanne Wolden3
1Department of Radiation Oncology and Neurosurgery, Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.
Pediatric Blood & Cancer
|April 5, 2021
Summary
Radiosurgery and brachytherapy offer potential for reirradiation in pediatric oncology, but careful consideration of organ tolerance and long-term complications is crucial for recurrent tumors.
Area of Science:
- Pediatric Oncology
- Radiation Oncology
Background:
- Radiosurgery and brachytherapy are underutilized in pediatric oncology.
- These techniques are primarily considered for reirradiation of recurrent or metastatic pediatric tumors.
Purpose of the Study:
- To review the current literature on reirradiation using radiosurgery and brachytherapy in pediatric patients.
- To assess the potential benefits and risks associated with these techniques in managing recurrent pediatric cancers.
Main Methods:
- Literature review of studies involving radiosurgery and brachytherapy in pediatric oncology.
- Analysis of data concerning reirradiation for recurrent or metastatic tumors in children.
Main Results:
- Reirradiation in pediatric patients presents challenges due to critical organ tolerance.
- Long-term, dose-dependent complications are a significant concern in pediatric reirradiation.
Conclusions:
- Radiosurgery and brachytherapy show promise but require cautious application in pediatric reirradiation.
- Further research is needed to optimize the use of these advanced radiation techniques while minimizing risks in children.
