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Updated: Nov 9, 2025

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
[Genetic screening of prospective parents]
Vibe Madsen Smed, Olav Bennike Bjørn Petersen, Anne-Marie Axø Gerdes
1Laura.kirstine.soenderberg.roos@regionh.dk.
Abstract:
Risk of genetic diseases with autosomal recessive or X-linked inheritance can be unknown to prospective parents until an affected child is born. New technology has enabled carrier screening for hundreds of genetic diseases (expanded carrier screening, ECS). I Denmark, each year estimated 100-180 children are born affected with a serious condition which could have been detected with ECS of the parents. This review describes the considerations and perspectives of a systematic genetic screening programme for prospective parents in the Danish healthcare system.
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