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Risk of emergency surgery for complicated appendicitis: Japanese nationwide study
Takeshi Yamada1, Hideki Endo2, Hiroshi Hasegawa3
1Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School Tokyo Japan.
Insights
Complicated appendicitis (CA) surgery has higher complication rates than uncomplicated appendicitis (UA). Elective appendectomy (EA) shows significantly lower risks for all appendicitis types.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Public Health
Background:
- Appendicitis is classified as complicated (CA) or uncomplicated (UA).
- Interval appendectomy (IA) reduces complications in pediatric CA cases.
- The comparative risk of emergency surgery for CA versus UA in adults requires clarification.
Purpose of the Study:
- To compare complication and mortality rates between emergency surgery for CA and UA in adults.
- To evaluate the risk associated with elective appendectomy (EA) for chronic/recurrent appendicitis.
Main Methods:
- Retrospective cohort study of adult appendectomy patients from the National Clinical Database (2014-2016).
- Groups included: CA (emergency surgery), UA, and EA (elective surgery).
- Primary outcomes: 30-day all morbidity, serious morbidity, and mortality.
Main Results:
- The CA group had significantly higher rates of all morbidity, serious morbidity, and mortality compared to the UA group.
- The EA group demonstrated significantly lower rates of all outcomes compared to both CA and UA groups.
- Study included 109,256 patients: 14,798 CA, 86,876 UA, and 7,582 EA.
Conclusions:
- Emergency surgery for complicated appendicitis (CA) presents a higher risk to adult patients.
- Elective appendectomy (EA) is associated with significantly lower risks compared to emergency surgery for both CA and UA.
Aim:
Appendicitis is divided into two categories: complicated appendicitis (CA) and uncomplicated appendicitis (UA). In pediatric patients with CA, the use of interval appendectomy (IA), which is non-operative management followed by elective surgery, has decreased the number of postoperative complications. Before discussing the merit of IA for adult patients, we need to clarify whether the frequency and seriousness of the complication rate after emergency surgery is higher for CA than for UA.
Methods:
This retrospective cohort study included adult patients who underwent appendectomy and who were registered in the National Clinical Database (NCD) from 2014 to 2016. Patients with CA who underwent emergency appendectomy comprised the CA group. Patients with UA comprised the UA group. Patients with chronic or recurrent appendicitis who underwent elective appendectomy comprised the elective appendectomy (EA) group. Primary outcomes were all morbidity, serious morbidity, and mortality within 30 days after appendectomy.
Results:
We included 109 256 patients in the study: 14 798 CA, 86 876 UA, and 7582 EA patients. Compared with the UA group, the rates of all morbidity, serious morbidity, and mortality were significantly higher in the CA group. All morbidity, serious morbidity, and mortality rates were significantly lower in the EA group than in the other two groups.
Conclusions:
We confirmed that emergency surgery for CA places the patient at relatively higher risk. We also showed that the risk associated with EA is significantly lower than that for the other methods.
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