Risk of emergency surgery for complicated appendicitis: Japanese nationwide study

Takeshi Yamada1, Hideki Endo2, Hiroshi Hasegawa3

  • 1Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School Tokyo Japan.

Insights

Complicated appendicitis (CA) surgery has higher complication rates than uncomplicated appendicitis (UA). Elective appendectomy (EA) shows significantly lower risks for all appendicitis types.

Area of Science:

  • Gastroenterology
  • Surgical Outcomes
  • Public Health

Background:

  • Appendicitis is classified as complicated (CA) or uncomplicated (UA).
  • Interval appendectomy (IA) reduces complications in pediatric CA cases.
  • The comparative risk of emergency surgery for CA versus UA in adults requires clarification.

Purpose of the Study:

  • To compare complication and mortality rates between emergency surgery for CA and UA in adults.
  • To evaluate the risk associated with elective appendectomy (EA) for chronic/recurrent appendicitis.

Main Methods:

  • Retrospective cohort study of adult appendectomy patients from the National Clinical Database (2014-2016).
  • Groups included: CA (emergency surgery), UA, and EA (elective surgery).
  • Primary outcomes: 30-day all morbidity, serious morbidity, and mortality.

Main Results:

  • The CA group had significantly higher rates of all morbidity, serious morbidity, and mortality compared to the UA group.
  • The EA group demonstrated significantly lower rates of all outcomes compared to both CA and UA groups.
  • Study included 109,256 patients: 14,798 CA, 86,876 UA, and 7,582 EA.

Conclusions:

  • Emergency surgery for complicated appendicitis (CA) presents a higher risk to adult patients.
  • Elective appendectomy (EA) is associated with significantly lower risks compared to emergency surgery for both CA and UA.
Abstract

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