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CD200R1L is a functional evolutionary conserved activating receptor in human neutrophils

M Inês Pascoal Ramos1, Can Keşmir2, Jorn E Stok1

  • 1Center for Translational Immunology, Dept. Immunology, University Medical Center Utrecht, Utrecht University, Oncode Institute, Utrecht, The Netherlands.

Journal of Leukocyte Biology
|April 22, 2021
PubMed
Summary

CD200R1L, a newly identified activating receptor on human neutrophils, triggers reactive oxygen species (ROS) production. Its evolutionary conservation across vertebrates suggests a vital role in pathogen defense.

Keywords:
NETosisphylogenyreactive oxygen species

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