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Updated: Nov 8, 2025

Design, Synthesis, and Photochemical Properties of Clickable Caged Compounds
Published on: October 15, 2019
De novo approach for the synthesis of water-soluble interlocked and non-interlocked organic cages
Debsena Chakraborty1, Ritwik Modak1, Prodip Howlader1
1Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore-560012, India. psm@iisc.ac.in.
Abstract:
Research on self-assembled metallosupramolecular architectures has bloomed in recent times. Analogous metal-free organic architectures with water solubility are highly challenging. We report here a unique class of triazine based immidazolium water-soluble metal-free interlocked organic cage (1), which was synthesized in a one-pot reaction without using dynamic covalent chemistry and without any chromatographic separation. An analogous non-interlocked cage (2) was also successfully achieved by steric control using different positional isomers of the building blocks.
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