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Lentinellic acid, a biologically active protoilludane derivative from Lentinellus species (Basidiomycetes)
1LB Biotechnologie der Universität, Kaiserslautern, Bundesrepublik Deutschland.
Abstract:
A new antimicrobial and cytotoxic sesquiterpenoid, lentinellic acid, has been isolated from submerged cultures of Lentinellus ursinus and L. omphalodes. The structure of the antibiotic was elucidated by spectroscopic methods and a single crystal X-ray analysis. 1 may be formed biogenetically by condensation of a protoilludane aldehyde 4 with a malonate unit.