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Updated: Nov 8, 2025

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Published on: September 1, 2016
Opioids in Hemodialysis Patients.
Sahir Kalim1, Karen S Lyons2, Sagar U Nigwekar1
1Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Patients with end-stage kidney disease on hemodialysis often experience chronic pain and opioid use. Careful risk-benefit assessment is crucial for safe opioid prescribing in this vulnerable group.
Area of Science:
- Nephrology
- Pain Management
- Pharmacology
Background:
- Chronic pain is common in hemodialysis patients.
- Opioid use presents significant risks in this population.
- Existing studies highlight vulnerabilities to opioid complications.
Purpose of the Study:
- To review literature on opioid prescribing in hemodialysis patients.
- To discuss clinical implications of opioid use.
- To outline current research directions.
Main Methods:
- Literature review of patient-oriented studies.
- Analysis of clinical experience.
- Synthesis of existing research.
Main Results:
- High prevalence of chronic pain and opioid use in hemodialysis.
- Increased vulnerability to opioid-related complications.
- Need for balanced pain management strategies.
Conclusions:
- Opioid prescribing requires careful risk-benefit evaluation in hemodialysis.
- Further research is needed to guide safe practices.
- A balanced approach to pain management is essential.
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