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Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
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Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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Neuro-Oncologic Emergencies.

Zachary D Threlkeld1, Brian J Scott2

  • 1Division of Neurocritical Care, Department of Neurology, Stanford University School of Medicine, 300 Pasteur Drive MC 5778, Stanford, CA 94305, USA.

Neurologic Clinics
|April 26, 2021
PubMed
Summary
This summary is machine-generated.

Cancer treatments can impact the nervous system, leading to emergencies like cerebral edema and seizures. Prompt recognition and team collaboration are key for managing these neuro-oncologic emergencies effectively.

Keywords:
CAR-T cell neurotoxicityChemotherapy side effectIschemic strokeMetastatic epidural spinal cord compressionNeuro-oncology prognosisNeurologic immune-related adverse eventsStatus epilepticus

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Area of Science:

  • Neuro-oncology
  • Neurology
  • Cancer Therapy

Background:

  • Cancer and its treatments can significantly affect the nervous system.
  • Neurologic complications can present as medical emergencies, including cerebral edema, increased intracranial pressure, cerebrovascular events, status epilepticus, and epidural spinal cord compression.
  • While often mild, cancer therapy-related neurologic side effects can occasionally lead to severe illness.

Purpose of the Study:

  • To summarize the spectrum of neurologic complications associated with cancer and cancer therapies.
  • To highlight emergency presentations of neuro-oncologic conditions.
  • To emphasize the importance of prompt management for immunotherapies' neurologic side effects.

Main Methods:

  • Review of common and emergency neurologic complications in cancer patients.
  • Discussion of management strategies for neuro-oncologic emergencies.
  • Analysis of neurologic side effects from various cancer therapies, including immunotherapies.

Main Results:

  • Cancer and therapies can cause diverse neurologic issues, with some presenting as emergencies.
  • Immunotherapies can induce autoimmune-related neurologic side effects, typically responsive to immunosuppression.
  • Effective emergency management relies on early detection and interdisciplinary collaboration.

Conclusions:

  • Neuro-oncologic emergencies require prompt recognition and management.
  • Interdisciplinary teamwork and patient-centered decision-making are crucial for optimal outcomes.
  • Understanding and addressing the neurologic impact of cancer therapies is essential for patient care.