Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

71
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
71
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

688
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
688
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

59
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
59
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

63
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
63
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

55
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
55
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

96
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
96

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perception of Technology to Support Medication Management Among Community-dwelling African American Older Adults.

The Senior care pharmacist·2026
Same author

Trajectories of Treatment Disruption for Chronic Outpatient Medications for U.S. Veterans During Drug Shortages.

Pharmacoepidemiology and drug safety·2026
Same author

Exploring needs and perceptions about telemental healthcare among Veterans with spinal cord injuries, a qualitative study.

Journal of behavioral medicine·2026
Same author

Innovative Sensor-Based Approaches for Assessing Neurodegenerative Diseases: A Brief State-of-the-Art Review.

Sensors (Basel, Switzerland)·2025
Same author

Physiologic Differences in Vital Signs and Urine Tests in Spinal Cord Injury and the Effects on Urinary Tract Infection Diagnosis.

American journal of physical medicine & rehabilitation·2025
Same author

Developing a Maternal Health Education and Research Training Program for High School, Pharmacy, and Health Sciences Students.

International journal of environmental research and public health·2025

Related Experiment Video

Updated: Nov 8, 2025

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.4K

Building Community-Engaged Multidisciplinary Partnerships to Improve Medication Management in Elderly Patients With

Ivy O Poon1, Felicia Skelton2,3, Lena R Bean4

  • 1Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX.

Journal of Patient-Centered Research and Reviews
|April 26, 2021
PubMed
Summary

Engaging minority elderly patients in research improved medication safety strategies. Patient input identified concerns about drug ads and interactions, favoring face-to-face counseling for better outcomes.

Keywords:
adverse reactionsdrugselderlymultiple chronic conditionspatient-centered carepolypharmacyside effects

More Related Videos

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.8K

Related Experiment Videos

Last Updated: Nov 8, 2025

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.4K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.8K

Area of Science:

  • Gerontology
  • Health Services Research
  • Patient-Centered Outcomes Research

Background:

  • Adverse drug events (ADEs) prevention research is often researcher-driven, lacking patient involvement.
  • Minority elderly patients with multiple chronic conditions face unique medication safety challenges.

Purpose of the Study:

  • To engage minority elderly patients in developing research questions and strategies for improving medication safety.
  • To incorporate patient perspectives into the research process for more effective interventions.

Main Methods:

  • Recruited elderly patients (≥65 years) with ≥7 chronic medications from a historically African American community in Houston, Texas.
  • Convened a multidisciplinary workgroup including patients, caregivers, physicians, pharmacists, nurses, health educators, and social workers.
  • Utilized patient-centered outcomes research engagement principles, conducted an environmental scan, and presented findings at a community town hall.

Main Results:

  • 3 patients and 1 caregiver participated in 5 workgroup meetings; 74 seniors attended a town hall, and 69 completed surveys.
  • Top concerns included doubts about drug advertisements (79%) and drug interactions (70%).
  • 88% preferred face-to-face counseling over virtual methods, informing 3 grant proposals.

Conclusions:

  • This study offers a roadmap for patient-centered, multidisciplinary research in medication safety.
  • Patient engagement is crucial for refining research strategies and minimizing drug-related problems.
  • Findings highlight the need for culturally sensitive, accessible medication counseling methods.