Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous

Wenting Cheng1, Lei Zhou2, Kai Hu3

  • 1Department of Clinical Laboratory, Nanjing Gaochun People's Hospital, Nanjing 211300, China.

ACS Sensors
|April 28, 2021
PubMed
Summary

A novel molecular probe targets cancer-associated extracellular matrix (ECM) enzymes like lysyl oxidase (LOX) by modulating their activity. This biomimetic biosensor offers new insights into ECM enzyme function and cancer invasiveness.