Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

Area of Science:

• Biochemistry
• Enzymology
• Pharmacology

Background:

• Bromelain is a proteolytic enzyme complex derived from pineapple stems.
• It comprises several thiol endopeptidases and is purified through various extraction methods.

Purpose of the Study:

• To review the diverse healthcare applications of bromelain.
• To explore its low toxicity and potential interactions with nanoparticles.
• To highlight areas for future research.

Main Methods:

• Literature review of existing studies on bromelain.
• Analysis of reported therapeutic effects and biochemical properties.
• Examination of bromelain's relationship with nanotechnology.

Main Results:

• Bromelain exhibits significant anti-inflammatory properties.
• Potential anticancer and antimicrobial activities have been identified.
• Positive effects on respiratory, digestive, circulatory, and immune systems are noted, along with benefits for arthritis symptoms.

Conclusions:

• Bromelain is a versatile enzyme with established and potential therapeutic uses.
• Its low toxicity and synergy with nanoparticles warrant further investigation.
• Extensive research is recommended to fully realize its healthcare potential.