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A review on B/A measurement methods with a clinical perspective
Anastasiia Panfilova1, Ruud J G van Sloun1, Hessel Wijkstra1
1Electrical Engineering Department, Faculty of Electrical Engineering, Eindhoven University of Technology, Groene Loper 35612 AE, Eindhoven, The Netherlands.
The Journal of the Acoustical Society of America
|May 4, 2021
Summary
The nonlinear ultrasound parameter B/A offers valuable diagnostic insights but faces clinical limitations. This review explores promising measurement techniques for B/A estimation in tissues, aiming to overcome current challenges.
Area of Science:
- Biomedical Engineering
- Acoustics
- Medical Imaging
Background:
- The nonlinear parameter B/A is a sensitive indicator of medium properties like temperature and structure.
- Current limitations in measurement and imaging techniques hinder the clinical application of B/A as a diagnostic tool.
- Nonlinear ultrasound principles are fundamental to understanding B/A estimation methods.
Purpose of the Study:
- To provide a comprehensive review of techniques for measuring the nonlinear ultrasound parameter B/A.
- To identify promising B/A measurement methods for clinical applications, particularly for liquid and tissue-like media.
- To summarize advancements, challenges, and future directions in B/A estimation.
Main Methods:
- Review of existing literature on nonlinear ultrasound measurement techniques.
- Analysis of methods for B/A parameter estimation in various media, including biological tissues.
- Discussion of the underlying physics and theoretical principles of nonlinear acoustics.
Main Results:
- Several techniques show promise for clinical B/A measurement, despite existing challenges.
- Progress in nonlinear ultrasound has been made, but clinical integration remains limited.
- Identification of key limitations in current B/A measurement and imaging approaches.
Conclusions:
- Further development of measurement and imaging techniques is crucial for clinical adoption of B/A.
- Promising methods for B/A estimation in tissues are highlighted, offering potential for improved diagnostics.
- This review serves as a guide for researchers and clinicians interested in nonlinear ultrasound diagnostics.
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