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Splanchnic circulation following coeliac plexus block
1Department of Anesthesiology, Kawasaki Medical School, Okayama, Japan.
Acta Anaesthesiologica Scandinavica
|May 1, 1988
Summary
Abdominal sympathectomy dilates splanchnic capacitance vessels, shifting blood volume to the splanchnic circulation. Resistance vessels in this area are minimally affected by this procedure.
Area of Science:
- Physiology
- Vascular Biology
- Autonomic Nervous System
Background:
- The splanchnic circulation, comprising capacitance and resistance vessels, is innervated by sympathetic nerve fibers.
- Understanding the role of sympathetic innervation is crucial for comprehending splanchnic and systemic hemodynamics.
Purpose of the Study:
- To investigate the impact of abdominal visceral sympathectomy on splanchnic circulation.
- To determine the subsequent effects of altered splanchnic circulation on systemic circulation.
Main Methods:
- Abdominal visceral sympathectomy was performed in mongrel dogs via coeliac plexus block using lidocaine.
- Hemodynamic parameters of systemic and splanchnic circulation were monitored and compared to a saline control group.
Main Results:
- Coeliac plexus block significantly decreased mean arterial pressure and cardiac index.
- Splanchnic blood flow, including portal vein and hepatic artery flow, decreased by 8-17%.
- Capacitance vessels in the splanchnic area were found to dilate, while resistance vessels showed minimal changes.
Conclusions:
- Abdominal sympathetic denervation leads to dilation of splanchnic capacitance vessels.
- This dilation causes a blood shift from systemic to splanchnic circulation.
- Splanchnic resistance vessels are largely unaffected by abdominal sympathectomy.