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Ventricular ejection fractions of linear transformation and ellipsoid models
J M Wattenbarger1, G H Templeton, G B Seibert
1Department of Medicine, University of Texas Health Science Center, Dallas 75235.
The American Journal of Physiology
|July 11, 1988
Summary
A linear transformation model accurately estimates ejection fractions in beating hearts, correlating well with actual measurements. This provides a reliable method for assessing cardiac function in vivo.
Area of Science:
- Cardiovascular Physiology
- Biomedical Engineering
- Medical Imaging
Background:
- Previous studies showed a linear relationship between eigenvolumes and balloon volumes in excised hearts.
- Assessing cardiac function in intact, beating hearts requires accurate ejection fraction measurement.
Purpose of the Study:
- To validate the linear transformation model for calculating ejection fractions in intact, contracting left ventricles.
- To compare ejection fractions from the linear transformation model with those from an established ellipsoidal model.
Main Methods:
- Biplane cinefluorography was used to analyze endocardial marker kinematics in 10 dogs.
- Linear regression analysis compared ejection fractions calculated by the linear transformation model and an ellipsoidal model.
Main Results:
- A high correlation coefficient (0.98) was found between the two models.
- The regression equation closely resembled the line of identity, indicating strong agreement.
Conclusions:
- Ejection fractions calculated using the linear transformation model are proportional to actual ejection fractions in beating left ventricles.
- This model offers a validated, non-invasive method for assessing cardiac function in vivo.