[Corrigendum] Cyclophilin D modulates cell death transition from early apoptosis to programmed necrosis induced by

Wei Tian1, Dong Xu1, Weidong Han2

  • 1Department of Surgical Oncology, The Second Affiliated Hospital, School of Medicine,Zhejiang University, Hangzhou 310009, P.R. China.

Insights

This corrigendum addresses errors in Figure 6, specifically the BCL-xl bands, which were mistakenly compiled from the GAPDH dataset. Re-experimentation confirmed the original study

Area of Science:

  • Molecular Biology
  • Cellular Signaling
  • Cancer Research

Context:

  • The original article investigated cellular signaling pathways relevant to cancer.
  • Figure 6 presented critical western blot data supporting the study's conclusions.
  • An anomaly was identified concerning the data presented in Figure 6.

Purpose:

  • To correct erroneous data in Figure 6 related to BCL-xl protein bands.
  • To address potential data duplication issues within Figure 6 and between Figures 5 and 6.
  • To provide a revised figure with accurate data and reaffirm the study's findings.

Summary:

  • Errors in the original Figure 6 involved the incorrect selection of BCL-xl bands from the GAPDH dataset.
  • Original western blot images were unavailable; therefore, experiments were repeated to corroborate results.
  • Revised Figure 6, containing newly generated data, is presented, confirming the original study's conclusions.

Impact:

  • Ensures the accuracy and integrity of the published scientific record.
  • Reaffirms the validity of the study's conclusions despite the data compilation error.
  • Provides corrected data for researchers utilizing or referencing this study in cancer research.

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