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Capillary blood sampling increases the risk of preanalytical errors in pediatric hospital care: Observational
Henrik Hjelmgren1,2, Anna Nilsson1,2, Ida H Myrberg2
1Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Insights
Capillary blood sampling in children has a higher risk of preanalytical errors compared to venous sampling. Increasing body weight and using fewer tubes can reduce these errors in pediatric blood collection.
Area of Science:
- Pediatric hospital care
- Clinical laboratory science
- Patient safety
Background:
- Preanalytical errors are a significant challenge in pediatric blood sampling.
- Understanding factors contributing to these errors is crucial for improving diagnostic accuracy and patient care.
Purpose of the Study:
- To compare the risk of preanalytical errors between capillary and venous blood sampling in pediatric patients.
- To identify specific factors associated with preanalytical errors in pediatric blood collection.
Main Methods:
- Observational study analyzing medical records and blood sampling surveys from 2014-2016.
- Multivariable logistic regression was used to calculate adjusted odds ratios (adj-OR) for preanalytical errors.
Main Results:
- 13% of 951 blood samples had preanalytical errors.
- Capillary blood sampling showed a significantly higher error rate (20%) compared to venous sampling (9.4%), with an adj-OR of 2.88.
- Multiple sample tube collection increased error risk, while higher child body weight demonstrated a protective effect, particularly for venous samples.
Conclusions:
- Capillary blood sampling significantly increases the risk of preanalytical errors in pediatric settings.
- Interventions such as prioritizing venous sampling and optimizing capillary collection techniques, alongside considering patient weight and tube usage, can mitigate these errors.
Purpose:
The blood sampling procedure is complex and prone to failure, as reflected by preanalytical errors in pediatric hospital care. The primary aim was to evaluate if the risk of preanalytical errors was higher with capillary blood sampling than with venous blood sampling, and secondary, explore specific factors associated with preanalytical errors, both overall and stratified by capillary and venous blood sampling.
Design And Methods:
This observational pediatric hospital study collected outcomes from medical records and blood sampling surveys from year 2014 to 2016. The risk of preanalytical errors was analyzed with adjusted-odds ratio (adj-OR) by multivariable logistic regression with 95% confidence intervals (CIs).
Results:
Overall, 128 (13%) preanalytical errors were identified among 951 blood samples. The proportion and adj-OR of errors was significantly higher in capillary compared with venous blood samples, 72 (20%) of 354 versus 56 (9.4%) of 597, p = .001, adj-OR 2.88 (CI 1.79-4.64). Blood collection with multiple sample tubes was significantly associated with increased risk of preanalytical errors (n = 97 of 601, 16%), while log weight (kg) significantly decreased the risk of preanalytical errors adj-OR 0.66 (CI 0.50-0.86), indicating a protective effect of increasing weight. However, stratified analyses indicated a protective effect of increasing log weight for venous blood sampling adj-OR 0.52 (CI 0.38-0.72), but not capillary blood sampling, adj-OR 1.08 (CI 0.76-1.55).
Conclusion:
This study indicates that capillary blood sampling collection increases the risk of preanalytical errors. Further, a child's increasing body weight reduced the risk of preanalytical errors, while multiple sample tube collections significantly increased the risk of preanalytical errors.
Practice Implications:
This new information may help nurses improve their knowledge concerning blood sampling collection in pediatrics. Altogether, this study also indicates that implementing more venous blood sampling and improve the cases of capillary sampling could reduce the number of preanalytical errors in pediatric hospitals.
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