Intraoperative BOLD-fMRI Cerebrovascular Reactivity Assessment

Area of Science:

• Neuroscience
• Medical Imaging
• Hemodynamics

Background:

• Cerebrovascular reactivity (CVR) is crucial for brain health, with impairments linked to diseases like stroke and gliomas.
• Blood oxygenation-level dependent (BOLD) techniques offer high-resolution CVR assessment.
• Intraoperative CVR monitoring is an emerging field with limited investigation.

Purpose of the Study:

• To evaluate the feasibility of intraoperative BOLD-CVR monitoring in neurosurgical patients.
• To explore the potential applications and future developments of this novel technique.

Main Methods:

• Implementation of intraoperative BOLD-CVR monitoring.
• Application in vascular and oncologic neurosurgical cases.
• Feasibility assessment and result discussion.

Main Results:

• Successful application of intraoperative BOLD-CVR in initial neurosurgical cases.
• Demonstrated feasibility of the technique for real-time hemodynamic assessment.
• Identified potential for further development and clinical integration.

Conclusions:

• Intraoperative BOLD-CVR is a feasible technique for assessing brain hemodynamics during neurosurgery.
• This method holds promise for improving patient outcomes in vascular and oncologic neurosurgery.
• Further research is warranted to optimize and expand the use of intraoperative BOLD-CVR.