Logistics of automated plasma collection

Area of Science:

• Blood Component Collection
• Transfusion Medicine
• Biopharmaceutical Production

Background:

• Plasma fractionation is crucial for producing vital proteins like Factor VIII and albumin.
• The Canadian Red Cross seeks national self-sufficiency in plasma production within four years to meet increasing demand.
• Efficient utilization of automated plasmapheresis and human resources is key to cost-effective plasma product generation.

Purpose of the Study:

• To assess the operational capacity of automated plasmapheresis machines at the Ottawa Centre.
• To determine the necessary staffing levels for safe and efficient operation of plasmapheresis procedures.
• To evaluate donor availability, reliability, and motivations to support an escalated plasma donation program.

Main Methods:

• An assessment was conducted at the Ottawa Centre to evaluate machine throughput and staffing requirements.
• Data on donor availability, reliability, and reasons for donation were collected.
• Staff and donor acceptance of automated plasmapheresis equipment was assessed.

Main Results:

• Four automated plasmapheresis devices can be efficiently operated by one nurse and one clinic assistant.
• This staffing model can process 32 donors per day, with an average donation time of 27 minutes for 500 ml of plasma.
• The donor population demonstrated availability and high interest in plasma donation.

Conclusions:

• The study indicates feasibility for increased plasma production through optimized use of automated plasmapheresis.
• Donor availability and interest support the goal of national plasma self-sufficiency.
• Logistical challenges in donor scheduling require focused attention for successful program escalation.