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Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
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Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

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Contrast-enhanced ultrasound of the kidneys and adrenals in children

Susan J Back1,2, Patricia T Acharya3, Richard D Bellah4,5

  • 1Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA. backs@email.chop.edu.

Pediatric Radiology
|May 12, 2021
PubMed

Insights

Contrast-enhanced ultrasound (CEUS) shows promise for pediatric kidney and adrenal gland evaluations, though it remains an off-label use. Extrapolating adult data suggests significant opportunities for clinical application in children.

Area of Science:

  • Pediatric Radiology
  • Medical Imaging
  • Ultrasound Technology

Background:

  • Contrast-enhanced ultrasound (CEUS) applications in pediatrics are expanding.
  • Intravenous contrast agents for pediatric kidney and adrenal gland evaluation are off-label.
  • Established adult CEUS knowledge can inform pediatric use.

Purpose of the Study:

  • To review current pediatric CEUS experience for kidneys and adrenal glands.
  • To identify potential clinical uses of CEUS in pediatric patients.
  • To bridge the gap between adult and pediatric CEUS applications.

Main Methods:

  • Review of current literature and clinical experience.
  • Extrapolation of established adult kidney CEUS findings to pediatric cases.
  • Focus on applications for pediatric renal and adrenal imaging.

Main Results:

  • Pediatric kidney CEUS applications mirror adult uses: ischemic disorders, tumor differentiation, lesion evaluation, pyelonephritis, and abscesses.
  • Pediatric adrenal CEUS is limited, primarily for trauma assessment and hemorrhage vs. mass differentiation.
  • Significant potential exists for pediatric CEUS in renal and adrenal imaging.

Conclusions:

  • Pediatric CEUS for kidneys and adrenal glands offers valuable diagnostic opportunities.
  • Further research and guideline development are needed for off-label pediatric CEUS use.
  • CEUS can enhance the evaluation of pediatric renal and adrenal conditions.

Keywords:
Adrenal glandsChildrenContrast-enhanced ultrasoundKidneysUltrasoundUltrasound contrast agents

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