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Related Experiment Video

Updated: Nov 6, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

[Prostate biopsy 2021: current management].

Florian Wagenlehner¹, Gernot Bonkat², Adrian Pilatz¹

¹Justus-Liebig-Universität Gießen, Klinik für Urologie, Kinderurologie und Andrologie, Giessen.

Aktuelle Urologie

|May 12, 2021

Summary

This summary is machine-generated.

To reduce infectious complications from prostate biopsies, opt for transperineal biopsy. If transrectal biopsy is necessary, use non-fluoroquinolone antibiotics and intrarectal cleaning with povidone-iodine.

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Published on: October 10, 2019

Area of Science:

Urology
Infectious Diseases
Antimicrobial Resistance

Background:

Rising infectious complications post-prostate biopsy linked to fluoroquinolone resistance.
Fluoroquinolone use for prophylaxis is now restricted in Germany.
EAU guideline group reviewed randomized controlled trials (RCTs) on prostate biopsy infection prevention.

Purpose of the Study:

To evaluate strategies for reducing infectious complications following prostate biopsy.
To provide evidence-based recommendations for antibiotic prophylaxis in prostate biopsies.

Main Methods:

Meta-analysis of randomized controlled trials (RCTs).
Comparison of infectious complication rates between transperineal and transrectal prostate biopsy techniques.
Evaluation of different antibiotic prophylactic strategies.

Main Results:

Transperineal prostate biopsy significantly reduces infectious complications compared to transrectal biopsy.
For transrectal biopsy, intrarectal povidone-iodine cleaning and non-fluoroquinolone antibiotic prophylaxis are recommended.
RCT data supports aminoglycosides, third-generation cephalosporins, and fosfomycin trometamol for prophylaxis.

Conclusions:

Transperineal biopsy is the preferred method to minimize infectious risks.
Alternative antibiotic prophylaxis strategies are essential due to fluoroquinolone resistance.
Evidence supports specific non-fluoroquinolone antibiotics for infection prevention.