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Updated: Nov 5, 2025

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Analyzing Mitochondrial Morphology Through Simulation Supervised Learning
Published on: March 3, 2023
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Simulation-to-real domain adaptation with teacher-student learning for endoscopic instrument segmentation
Manish Sahu1, Anirban Mukhopadhyay2, Stefan Zachow3
1Zuse Institute Berlin (ZIB), Berlin, Germany. sahu@zib.de.
Summary
This study presents a novel teacher-student learning method for segmenting surgical instruments in endoscopic videos. The approach effectively uses simulated and real data, improving accuracy in annotation-scarce environments.
Area of Science:
- Medical image analysis
- Computer-assisted surgery
- Machine learning in healthcare
Background:
- Automated surgical scene understanding requires accurate segmentation of surgical instruments in endoscopic videos.
- Fully supervised deep learning methods are hindered by the time-consuming manual annotation process by clinical experts.
Purpose of the Study:
- To develop a teacher-student learning approach for unsupervised domain adaptation in endoscopic image segmentation.
- To address the challenge of segmenting surgical instruments using limited annotated data by leveraging both simulated and real endoscopic video streams.
Main Methods:
- A teacher-student learning framework was introduced, jointly learning from annotated simulation data and unlabeled real endoscopic data.
- The method focuses on unsupervised domain adaptation to bridge the gap between simulation and real-world endoscopic images.
Main Results:
- The proposed framework demonstrated superior performance compared to existing methods on three endoscopic instrument segmentation datasets.
- Analysis identified key factors influencing performance, revealing the strengths and limitations of the approach.
Conclusions:
- The approach effectively utilizes unlabeled real endoscopic video frames to enhance generalization performance.
- This work advances the goal of effective surgical instrument segmentation in settings with limited annotations, moving closer to practical applications.

