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Updated: Nov 5, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
(Chemo)Radiotherapy-Immunotherapy Combinations: Time to Get Tailored?
Michele Mondini1, Eric Deutsch1,2
1Gustave Roussy, Université Paris-Saclay, INSERM U1030, Villejuif, France. eric.deutsch@gustaveroussy.fr michele.mondini@gustaveroussy.fr.
Abstract:
Chemoradiotherapy is considered an immunogenic anticancer treatment. Data obtained during the course of chemoradiotherapy treatment of patients with cervical cancer show heterogeneous changes in the tumor immune landscape, highlighting the need for patient selection to rationally design successful combined immunotherapies. Blood-based biomarkers could be valuable to perform such stratification.See related article by Chen et al., p. 3990.
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