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Lea Aurora Cupul-Uicab1, José Ángel Hernández-Mariano2, Argelia Vázquez-Salas3
1Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública. Cuernavaca, Morelos, México.. lea.cupul@insp.mx.
Salud Publica De Mexico
|May 14, 2021
Summary
Pregnancy outcomes for mothers with COVID-19 show increased risks of C-sections and preterm birth. Neonates faced higher rates of low birth weight and neonatal intensive care unit admissions due to SARS-CoV-2.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Infectious Diseases
Background:
- COVID-19 poses potential risks to pregnant individuals and newborns.
- Understanding maternal and neonatal effects is crucial for clinical management.
Purpose of the Study:
- To synthesize scientific evidence on maternal and neonatal outcomes of COVID-19 during pregnancy.
- To assess the risks associated with SARS-CoV-2 infection in pregnancy.
Main Methods:
- Conducted a rapid Cochrane review and meta-analysis.
- Analyzed proportions and odds ratios (OR) for various outcomes.
Main Results:
- Common maternal events included mechanical ventilation and ICU admission; obesity and asthma were frequent comorbidities.
- COVID-19 in pregnancy was associated with higher rates of C-sections (OR=6.7) and preterm birth (OR=2.9).
- Neonatal outcomes included low birth weight, prematurity, and SARS-CoV-2 positivity (14%), with increased neonatal ICU admissions (OR=5.9).
Conclusions:
- Evidence on adverse COVID-19 effects during pregnancy is limited.
- Potential health risks to the mother-neonate dyad exist, particularly concerning C-sections and prematurity.
- Further research is needed to fully elucidate the long-term impacts.