Related Experiment Video
Updated: Nov 5, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis
Ahmed Arafa1,2, Xiaowen Wang1, Jia-Yi Dong1
1Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Abstract:
Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies.Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%).Conclusion: MS is not associated with PE.
Related Concept Videos
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Mitral Valve Prolapse III: Nursing Management
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...

