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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

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Cardiac myxosarcoma: A case report.

Manouchehr Hekmat¹, Alireza Omidi Farzin¹, Zahra Ansari Aval¹

¹Department of Cardiac Surgery, Modarres Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Caspian Journal of Internal Medicine

|May 20, 2021

Summary

Cardiac myxosarcoma is a rare malignant tumor often mistaken for benign myxoma. This case highlights the difficulty in diagnosis and the poor prognosis of myxosarcoma, emphasizing the need for advanced imaging.

Keywords:

Myxosarcoma Transthoracic Echocardiogram (TTE)

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Area of Science:

Cardiovascular Pathology
Surgical Oncology

Background:

Cardiac myxosarcoma is a rare primary cardiac malignancy with a poor prognosis, distinct from the generally benign myxoma.
Differentiating myxosarcoma from myxoma is challenging due to similar appearances and pathological findings.
Myxosarcoma requires aggressive treatment including surgery and chemoradiotherapy, unlike myxoma which is typically treated with surgery alone.

Observation:

A 58-year-old patient presented with congestive heart failure due to a left atrial mass.
Transthoracic echocardiogram revealed a large, mobile left atrial mass.
Initial histopathology after surgical resection suggested myxoma.

Findings:

Post-operative laparatomy revealed extensive abdominal metastatic masses, confirming a diagnosis of myxosarcoma.
The patient experienced progressive gastrointestinal bleeding and expired shortly after surgery.
The case underscores the diagnostic challenges and aggressive nature of cardiac myxosarcoma.

Implications:

Accurate differentiation between cardiac myxoma and myxosarcoma is critical for appropriate treatment and prognosis.
Advanced imaging modalities like magnetic resonance imaging may aid in identifying malignancy.
This case highlights the potential for misdiagnosis and the aggressive metastatic potential of cardiac myxosarcoma.