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Updated: Nov 4, 2025
08:32
Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
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Using Voice Change as an Indicator of Dysphagia: A Systematic Review.
Karoline Weber Dos Santos1, Esther da Cunha Rodrigues2, Rafaela Soares Rech2
1Cristo Redentor Hospital/Conceição Hospital Group, 20, Domingos Rubbo Street, Porto Alegre, Rio Grande do Sul, 91040-000, Brazil. karolweber@gmail.com.
Dysphagia
|May 21, 2021
Summary
Post-swallow voice change is a common indicator for dysphagia risk. However, this review found significant heterogeneity in methods and high bias, preventing consensus on its accuracy for identifying swallowing deficits.
Area of Science:
- Speech-Language Pathology
- Clinical Diagnostics
- Swallowing Disorders
Background:
- Voice change after swallowing is a clinical sign suggesting potential dysphagia.
- Limited research exists on the agreement between voice changes and objective measures of swallow dysfunction.
Purpose of the Study:
- To systematically review evidence on the relationship between post-swallow vocal changes and dysphagia identified via Videofluoroscopic Swallow Study (VFSS).
Main Methods:
- Systematic review following PRISMA guidelines.
- Included 17 studies analyzing vocal changes and VFSS findings.
- Assessed methodological quality and risk of bias using QUADAS-2.
Main Results:
- Significant heterogeneity observed in voice analysis methods (acoustic, auditory-perceptual, or both) and parameters assessed.
- Forty-seven percent of studies had a high risk of bias due to lack of clarity and blinding in VFSS.
- Lack of standardization in food/liquid consistencies and VFSS outcome measures prevented direct comparison.
Conclusions:
- Due to methodological heterogeneity and high risk of bias, a consensus cannot be reached on using vocal evaluation as an accurate method for identifying swallowing alterations.
- Further research with standardized protocols is needed to establish the reliability of voice change as a dysphagia indicator.
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