Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ocular Surface Toxicity of Antibody-Drug Conjugates: Pathogenesis, Diagnosis, Grading, and Treatment of Ocular Adverse Effects.

Cornea·2026
Same author

Comparing Global Operating Room Waste Generated From Cataract, Corneal, and Conjunctival Surgeries.

Cornea·2026
Same author

Regenerative Ophthalmology: A Paradigm Change.

American journal of ophthalmology·2026
Same author

Standardized Classification System for Dysphotopsia Reporting.

Ophthalmology. Glaucoma·2026
Same author

Malignancy Risk after Ophthalmic Herpes Infection within a Diverse United States Cohort.

Ophthalmology·2026
Same author

Technological Interventions for Dry Eye Disease: A Systematic Review and Random-Effects Network Meta-analysis of 3-Month Outcomes.

Ophthalmology and therapy·2026
Same journal

Posterior Segment Pressurization With Intravitreal Balanced Salt Solution to Stabilize Anterior Chamber Gas During Endothelial Keratoplasty.

Cornea·2026
Same journal

Central Corneal Thickness Six Postoperative Months After DMEK or Triple-DMEK.

Cornea·2026
Same journal

Rebubbling and Graft Detachment in Pre-Descemet Endothelial Keratoplasty: A Prospective Study.

Cornea·2026
Same journal

Letter Regarding: ESCALÓN: A Prospective Randomized Trial of Corneal Endothelial Cell Therapy in Subjects With Corneal Edema.

Cornea·2026
Same journal

Osimertinib-Associated Benign Ocular Hyperpigmentation: A Case Report.

Cornea·2026
Same journal

Outcomes of Descemet Stripping Endothelial Keratoplasty in Eyes With Anterior Chamber Intraocular Lenses.

Cornea·2026
See all related articles

Related Experiment Video

Updated: Nov 4, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
10:46

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Published on: September 17, 2014

15.5K

The "Two-Flaps" Technique for Descemet Stripping Only.

Eyal Cohen1, Nizar Din, Michael Mimouni

  • 1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.

Cornea
|May 24, 2021
PubMed
Summary
This summary is machine-generated.

A new "two-flaps" technique using specialized forceps optimizes Descemet stripping only (DSO) by creating a precise descemetorhexis. This method enhances surgical outcomes and minimizes corneal scarring for better visual recovery.

More Related Videos

A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
12:36

A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1

Published on: July 22, 2022

4.8K
An “All-laser” Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

9.7K

Related Experiment Videos

Last Updated: Nov 4, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
10:46

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty

Published on: September 17, 2014

15.5K
A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
12:36

A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1

Published on: July 22, 2022

4.8K
An “All-laser” Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

9.7K

Area of Science:

  • Ophthalmology
  • Corneal Surgery

Background:

  • Descemet stripping only (DSO) success relies on precise descemetorhexis.
  • Achieving a centered, accurately sized, and smooth-bordered descemetorhexis is crucial for optimal DSO outcomes.
  • Existing techniques may pose challenges in achieving the ideal descemetorhexis.

Observation:

  • The
  • two-flaps
  • technique utilizes Gorovoy DSO forceps for descemetorhexis.
  • The forceps' flat surface facilitates creation of a 4-mm Descemet stripping with minimal stromal trauma.
  • This technique aims for a continuous curvilinear descemetorhexis, reducing risks of scarring and rhexis extension.

Findings:

  • Successfully applied in 11 cases under direct supervision.
  • Achieved the target 4-mm circumference descemetorhexis consistently.
  • Demonstrated no residual tags or significant stromal scarring, with successful central cornea clearing and endothelial cell repopulation.

Implications:

  • Provides a reproducible and trauma-free method for Descemet membrane peeling.
  • Optimizes descemetorhexis for enhanced DSO success.
  • Contributes to improved patient outcomes in endothelial keratoplasty procedures.