Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Luminescent Solar Concentrators Based on Lanthanide Bimetallic Red-Emitting Metal-Organic Framework.

Inorganic chemistry·2026
Same author

Development of a Light-Triggered Biotin-Bioorthogonal System for Targeted Anti-Tumor Therapy.

Journal of medicinal chemistry·2026
Same author

Progress in bioorthogonal chemistry for prodrug activation and imaging.

European journal of medicinal chemistry·2026
Same author

Interfacial stabilization of quantum dot/liquid crystal co-assemblies for efficient circularly polarized luminescence.

Chemical communications (Cambridge, England)·2026
Same author

Site-Engineered Corundum-Structured Aesthetic Composites for Alleviating Heat Accumulation to Mitigate Urban Heat Islands.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

The ancient E-ring in bacterial flagellar motors.

FEMS microbiology reviews·2026

Related Experiment Video

Updated: Nov 4, 2025

Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.4K

Highly efficient ratiometric nanothermometers based on colloidal carbon quantum dots.

Yi Han1, Yanran Liu1, Haiguang Zhao2

  • 1School of Basic Medicine, Qingdao University, No. 308 Ningxia Road, Qingdao 266071, P. R. China.

Journal of Materials Chemistry. B
|May 26, 2021
PubMed
Summary

We developed a novel carbon dot (C-dot) based optical nanothermometer for precise temperature sensing. This highly sensitive, self-calibrated sensor shows promise for nanoscale thermometry and intracellular temperature monitoring.

More Related Videos

Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays
07:13

Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays

Published on: June 28, 2024

1.7K
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

13.0K

Related Experiment Videos

Last Updated: Nov 4, 2025

Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.4K
Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays
07:13

Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays

Published on: June 28, 2024

1.7K
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

13.0K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Optical Sensors

Background:

  • Optical nanothermometers offer non-contact, high-resolution temperature measurements at micro- and nanoscales.
  • Existing sensors often contain heavy metals or lack sufficient sensitivity.
  • Carbon dots (C-dots) are emerging as promising nanomaterials for sensing applications.

Purpose of the Study:

  • To develop a highly sensitive, self-calibrated ratiometric thermal sensor using colloidal C-dots.
  • To investigate the temperature-dependent photoluminescence (PL) of C-dots for thermometry.
  • To demonstrate the sensor's capability for intracellular temperature monitoring.

Main Methods:

  • Synthesis and surface functionalization of colloidal C-dots.
  • Characterization of dual emission properties (band gap and surface-dominant).
  • Measurement of temperature-dependent photoluminescence (PL) response.
  • Evaluation of absolute thermal sensitivity and self-calibration.

Main Results:

  • C-dots exhibit dual emission with distinct temperature-dependent PL responses.
  • C-dots@OH demonstrated the highest absolute thermal sensitivity (-0.082 °C-1) among ratiometric thermosensors.
  • Successful monitoring of intracellular temperature variations (32-42 °C) in a single cell.

Conclusions:

  • Colloidal C-dots offer a highly sensitive and self-calibrated platform for nanoscale thermometry.
  • C-dots@OH show significant potential for precise intracellular temperature measurements.
  • The developed nanothermometer is suitable for applications in micro-opto-electronics, photonics, and biomedical sensing.