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Yeast As a Chassis for Developing Functional Assays to Study Human P53
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DNA-Bound p53-DNA-Binding Domain Interconverts between Multiple Conformations: Implications for Partner Protein

Sayan Bhattacharjee1, Sujoy Mukherjee1, Siddhartha Roy2

  • 1Department of Structural Biology and Bioinformatics, CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata 700032, India.

The Journal of Physical Chemistry. B
|May 27, 2021
PubMed
Summary

Hub proteins like p53 utilize dynamic conformational changes to interact with diverse partners. DNA binding induces these crucial protein dynamics, enabling p53

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