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[Infrared angiography in increased intraocular pressure]
1Klinik für Augenkrankheiten des Kantonsspitals St. Gallen.
Klinische Monatsblatter Fur Augenheilkunde
|May 1, 1988
Summary
Elevated intraocular pressure (IOP) significantly reduces blood flow in the choroid and optic disc, impacting both healthy eyes and glaucoma patients. This study quanties reduced fundus fluorescence under increased IOP.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Research
Background:
- Intraocular pressure (IOP) is a critical factor in eye health.
- Glaucoma is characterized by elevated IOP, potentially damaging the optic nerve.
- Fundus angiography visualizes ocular blood flow.
Purpose of the Study:
- To investigate the impact of elevated intraocular pressure (IOP) on ocular blood flow.
- To quantitatively assess changes in fundus fluorescence under varying IOP conditions.
- To compare the effects in healthy subjects and glaucoma patients.
Main Methods:
- Infrared fundus angiography performed on healthy and glaucoma subjects.
- IOP artificially increased by approximately 20 mmHg in a second imaging session.
- Computer-aided image analysis used to quantify contrast medium passage (fluorescence).
Main Results:
- A significant reduction in fundus fluorescence was observed in both healthy and glaucoma groups when IOP was elevated.
- The choroid showed the most pronounced decrease in fluorescence.
- The central retinal artery and optic disc exhibited a less pronounced, but still notable, reduction in fluorescence.
Conclusions:
- Elevated IOP markedly impairs ocular microcirculation, particularly in the choroid.
- Reduced blood flow may contribute to optic nerve damage in glaucoma.
- Infrared fundus angiography is a valuable tool for assessing hemodynamic changes in the eye related to IOP.