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Updated: Nov 4, 2025

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Incidental Liver Findings on Cross-sectional Imaging
Adam C Searleman1, Lejla Aganovic1, Cynthia S Santillan1
1Department of Radiology, University of California San Diego, UCSD Medical Center, 200 West Arbor Drive, #8756, San Diego, CA 92103, USA.
Incidental liver findings on imaging are common. This review helps radiologists identify benign conditions and suspicious lesions, guiding further evaluation with proposed algorithms.
Area of Science:
- Radiology
- Hepatology
- Medical Imaging
Background:
- Incidental hepatic findings are frequently detected during imaging of non-liver areas.
- Radiologists must effectively triage these findings for appropriate further evaluation.
- Distinguishing benign from potentially malignant lesions is crucial.
Purpose of the Study:
- To review common benign hepatic entities seen on various imaging modalities.
- To outline imaging features indicative of malignancy or requiring further investigation.
- To propose algorithms for guiding radiologist recommendations on incidental liver findings.
Main Methods:
- Review of common benign hepatic lesions across ultrasound, CT, and MRI.
- Analysis of imaging characteristics differentiating benign from suspicious findings.
- Development of two decision-making algorithms based on patient risk, lesion size, and imaging features.
Main Results:
- Common benign hepatic entities and their characteristic imaging features are presented.
- Imaging findings suspicious for malignancy are identified.
- Two algorithms are proposed to aid in the management of incidental hepatic abnormalities.
Conclusions:
- Effective triage of incidental liver findings is essential for patient care.
- Characteristic imaging features aid in differentiating benign from malignant hepatic lesions.
- Proposed algorithms assist radiologists in making informed recommendations for further evaluation.
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