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Related Experiment Video

Updated: Nov 3, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Newer Therapies in Psoriasis.

Justin W Marson¹, Margaret L Snyder², Mark G Lebwohl²

¹National Society for Cutaneous Medicine, New York, NY, USA.

The Medical Clinics of North America

|June 1, 2021

Summary

Psoriasis, a systemic inflammatory disease affecting 125 million globally, is increasingly managed with new systemic agents. These targeted therapies offer improved options beyond traditional topical treatments for psoriasis patients.

Keywords:

Aryl hydrocarbon receptor modulator Biologics Interleukins Janus kinase inhibitor Psoriasis Therapy Tumor necrosis factor-alpha Tyrosine kinase inhibitor

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Area of Science:

Dermatology
Immunology
Systemic Inflammatory Diseases

Background:

Psoriasis is a chronic systemic inflammatory condition impacting global health.
Historically managed with topical agents, psoriasis is now recognized as affecting multiple organ systems.
This paradigm shift necessitates advanced therapeutic strategies.

Purpose of the Study:

To review new and emerging systemic therapeutic agents for psoriasis.
To discuss the indications and nuances of these advanced treatments.
To highlight the evolution of psoriasis management.

Main Methods:

Literature review of recent studies on psoriasis therapeutics.
Analysis of clinical data for novel systemic agents.
Discussion of immunomodulating and targeted treatment mechanisms.

Main Results:

Development of numerous immunomodulating systemic agents.
Targeted mechanisms of action represent a significant advancement.
New agents offer improved management options for psoriasis.

Conclusions:

Psoriasis management is evolving towards systemic, targeted therapies.
New agents address the systemic nature of the disease.
Continued research is vital for optimizing psoriasis care.